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Patch clamp Product List and Ranking from 4 Manufacturers, Suppliers and Companies

Patch clamp Product List

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Nanion Technologies Japan Co., Ltd.

Nanion Technologies Japan Co., Ltd.

A large number of products we handle, such as the "auto patch clamp system," are featured!

This document introduces Nanion Technologies Japan Co., Ltd. It includes company overview, target users, and announcements about campaigns. Additionally, it features products we handle, such as the "Automated Patch Clamp System" and the "iPS-Derived Cardiomyocyte Measurement System." We encourage you to read it. 【Contents (partial)】 ■ Company Overview ■ Products ■ Target Users ■ Automated Patch Clamp and Manual Patch Clamp ■ Campaign Announcements *For more details, please refer to the PDF document or feel free to contact us.

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Nanion Technologies Catalog

Nanion Technologies Catalog

We have a domestic wet lab! Introducing systems such as the auto patch clamp system and measurement systems.

This catalog introduces the products handled by Nanion Technologies Japan, the Japanese subsidiary of a manufacturer of analysis devices for basic and drug discovery research. We offer a lineup that includes low, medium, and high-throughput automated patch clamp systems, as well as iPS-derived cardiomyocyte measurement systems. Additionally, we provide information on the target users, including pharmaceutical companies. [Contents (excerpt)] ■ Nanion Technologies Japan ■ Automated Patch Clamp Systems ■ Target Users ■ Automated Patch Clamp and Manual Patch Clamp ■ Port-a-Patch mini *For more details, please refer to the PDF document or feel free to contact us.

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High-throughput automated patch clamp system ION FLUX

High-throughput automated patch clamp system ION FLUX

We provide the simplicity of a plate reader for screening ion channels.

"ION FLUX" is a high-throughput automated patch clamp system that provides high processing capability and solutions for on-channel drug discovery and research. It is fully integrated and easy to use with the "simplicity of a plate reader," demonstrating excellent patch clamp performance. Additionally, Fluxion's trademark well plate microfluidic technology eliminates the need for pipetting, enabling continuous recording of cells. 【Features】 ■ Simple ■ Low cost ■ High throughput ■ Compatible with all applications ■ Suitable for ion channel research and analysis *For more details, please refer to the PDF document or feel free to contact us.

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1ch Auto Patch Clamp Port-a-Patch mini

1ch Auto Patch Clamp Port-a-Patch mini

A patch clamp system that incorporates a patch clamp amplifier, achieving miniaturization and reduction of installation costs, allowing for easy data acquisition and verification.

This is a world-class patch clamp system capable of performing gigaseal recordings, optimal for safety testing/toxicity testing/pharmacological testing/screening of compounds at the cellular level in the functional structural analysis of ion channels, research on related diseases, and drug development processes. ■ No experience with manual patch clamping or difficult operations required ■ No need for microscope/vibration isolation table/manipulator/Faraday cage/puller ■ 20 to 50 data points per day ■ Automation from gigaseal formation to whole cell formation ■ Compatible with voltage-dependent and ligand-dependent channels through pipetting ■ Measurement of action potentials using current clamp is also possible ■ Supports a wide range of applications, enabling rapid assay system development ■ Reduces compound adsorption with borosilicate glass chips

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1ch Auto Patch Clamp Port-a-Patch

1ch Auto Patch Clamp Port-a-Patch

A world-class patch clamp system that is easy to operate for anyone, allowing for simple data acquisition and verification.

This is a patch clamp system of the world's smallest class that can perform gigaseal recordings, optimal for safety testing/toxicity testing/pharmacological testing/screening of compounds at the cellular level in the functional structural analysis of ion channels, research on related diseases, and drug development processes. 【Features】 ■ No need for manual patch clamp experience or difficult operations ■ No need for microscope, vibration table, manipulator, Faraday cage, or puller ■ 20 to 50 data points per day ■ Automation from gigaseal formation to whole cell formation ■ Compatible with voltage-dependent, ligand-dependent, and temperature-dependent channels ■ Options available for research on channel rhodopsins and mechanosensitive channels using light stimulation ■ Measurement of action potentials using current clamp is also possible ■ Supports a wide range of applications and enables rapid assay system development ■ Reduces compound adsorption with borosilicate glass chips ■ Optional temperature control (10 to 50°C), capable of extracellular/intracellular perfusion ■ Can be integrated with amplifiers such as HEKA and Axon *For details, please refer to the catalog available for download in PDF.

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4ch/8ch Auto Patch Clamp Patchliner

4ch/8ch Auto Patch Clamp Patchliner

No pipetting operations are required during the experiment. It is equipped with a benchtop dispensing device that can automatically measure up to 48 cells continuously in an auto patch clamp system.

This is a tabletop-sized auto patch clamp system that can simultaneously measure up to 8 cells with giga-seal formation. With easy experimental setup, stable whole-cell recordings, and sophisticated software, it enables highly efficient compound ion channel screening. ■ Equipped with a dispensing device, allowing for fully automated experiments (measurements) ■ Simultaneous measurement of 4 cells / 8 cells (up to 48 cells can be measured continuously) ■ 250 to 600 data points per day ■ Automation from giga-seal formation to whole-cell formation ■ Compatible with voltage-dependent and ligand-dependent channels ■ Measurement of action potentials using current clamp is also possible ■ Dynamic clamp capability (optional) ■ Temperature control and extracellular/intracellular perfusion possible ■ Cooling plate allows for cooling of cells and compounds ■ Borosilicate glass chips reduce compound adsorption ■ Comes with excellent analysis software

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384ch Auto Patch Clamp SyncroPatch 384

384ch Auto Patch Clamp SyncroPatch 384

An automated patch clamp system capable of meeting all needs, from small-scale screening projects to high-throughput screening.

Designed to seamlessly integrate fully automated compound screening into the drug discovery process, it provides the best performance in high-throughput screening of ion channels in drug discovery, pharmacology, safety, pharmaceutical research and development, and exploratory screening departments. Additionally, by using the 32-well mode, it can be optimized for small-scale compound screening and projects. ■ Simultaneous measurement of 384 cells ■ 20,000 data points per day ■ High giga-seal success rate ■ Supports a variety of ion channel targets and enables rapid assay system development ■ Measurement of action potentials using current clamp is also possible ■ Extracellular/intracellular perfusion is possible ■ High-speed external solution exchange (up to 110 µl/s) is possible ■ Measurement section and 12 decks can be individually temperature controlled (temperature range: 10–37°C) ■ Compound plate preparation on the deck is possible ■ Single & multi-well chips available (in-house manufactured) ■ Borosilicate glass chips reduce compound adsorption ■ Approximately 8 hours of unmanned operation is possible ■ Comes with powerful analysis software ■ Validated system for CiPA

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[Measurement Example] TRPA1 | Port-a-Patch

[Measurement Example] TRPA1 | Port-a-Patch

We will introduce a case study of TRPA1 measurement using Port-a-Patch.

Application Note: TRPA1 activation by allyl isothiocyanate recorded on the Port-a-Patch *For more details, please refer to the PDF document or feel free to contact us.

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[Cell and Ion Channel Measurement Example] Automated Patch Clamp System

[Cell and Ion Channel Measurement Example] Automated Patch Clamp System

We would like to introduce examples of cell and ion channel measurements using our auto patch clamp system.

We have published examples of cell and ion channel measurements using our auto patch clamp system. * For more details, please refer to the PDF materials from the "Catalog" at the bottom of the page. * Please feel free to contact us for requests regarding product and application case introductions. * Application cases are continuously added and updated.

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Automated Patch Clamp System "QPatch II"

Automated Patch Clamp System "QPatch II"

Benchmark system in the fields of safety pharmacology and advanced electrophysiology research!

"QPatch II" is a fully automated patch clamp system that has further evolved to meet the future demands of ion channel research while maintaining the advantages of "QPatch." It allows for easier and faster operation with reduced cell usage, obtaining proven high-quality data. The new intuitive software interface reduces human error and facilitates staff reallocation. By equipping the gripper arm with a barcode reader and adopting a plate stacking method on the workbench, we have achieved faster and more stable automation of experiments. [Features] - Rapid and robust experimental system - CiPA and cardiac safety evaluation - Optimized cell preparation - Independent control of all cells - Balancing ease of use and efficiency *For more details, please refer to the PDF materials or feel free to contact us.

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Auto Patch Clamp System "Qube384"

Auto Patch Clamp System "Qube384"

Make drug discovery research more efficient! Early screening with high-precision patch clamp data.

The "Qube384" is an auto patch clamp system capable of unmanned operation for over 8 hours, thanks to its unique cell maintenance and automated cell preparation mechanisms. It features a dispenser equipped with 1,536 high-precision linear motors and grippers, ensuring accuracy and speed in experiments. Additionally, it measures ion channels with high throughput and precision, facilitated by 384 independent pairs of electrodes and amplifiers. 【Features】 ■ Fully integrated system ■ Fully automated cell preparation unit ■ Sophion amplifiers essential for high-precision experiments ■ High-spec internal PC for system operation and data collection ■ Temperature control *For more details, please download the PDF or feel free to contact us.

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[Paper Introduction] Cardiomyocytes｜SyncroPatch

[Paper Introduction] Cardiomyocytes｜SyncroPatch

I would like to introduce some papers related to SyncroPatch.

A modern automated patch-clamp approach for high throughput electrophysiology recordings in native cardiomyocytes

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Space-saving tabletop size semi-auto patch clamp system

Space-saving tabletop size semi-auto patch clamp system

High-precision electrophysiological data can be easily obtained by anyone! With 'QPatch Compact', no training, setup, or maintenance is required.

The "QPatch Compact" is a new system that combines the flexibility of manual patch clamping with the stability of automated patch clamping. All necessary parts are assembled and inspected so that it can be used immediately after being taken out of the box. Complicated setups such as vibration isolation tables, Faraday cages, microscopes, manipulators, electrode pullers, and perfusion systems are not required. Stability is ensured by separating the hard drive for the database and experimental execution software. 【Features】 ■ Easy access to electrophysiological data ■ No training required ■ Up to 8 experiments can be conducted simultaneously ■ Supports fixed potential/current recording ■ Temperature and pressure control compatible *For more details, please refer to the PDF materials or feel free to contact us.

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Sophion Research Grant Awardee

Sophion Research Grant Awardee

A discussion about important research being conducted at the Sophion facility in Copenhagen!

The recipients of the Sophion research grant are utilizing the grant to conduct research on chemotherapy drugs targeting Nav1.7 currents, further deepening their studies on sodium channels and cancer by using Sophion's automated patch clamp system. They are an assistant professor at Istanbul Medipol University and are currently affiliated with our laboratory in Copenhagen, conducting research alongside senior researcher Kim Boddum. We had a discussion about the research and its objectives. *For more detailed information, please refer to the related links. Feel free to contact us for further inquiries.*

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[Measurement Example] TRPM8 | Port-a-Patch

[Measurement Example] TRPM8 | Port-a-Patch

We will introduce a case study of TRPM8 measurement using Port-a-Patch.

Application Note: Cold activation of TRPM8 using the External Perfusion System and the Port-a-Patch *For more details, please refer to the PDF document or feel free to contact us.

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